HyStim

Conventions of modern society mostly call for us to be civilized in deed and manner throughout the course of daily lives, with the notable exception of athletic pursuit. It’s here, especially in the gym, where full-throttle, single-minded aggressive behavior is not only acceptable, but prized. If your goal is building muscle, lackadaisical simply won’t cut it.

To ensure these brief respites from the civilized world aren’t wasted with anything less than laser-like focus, we’ve created the pre-workout, brain-boosting formula HyStim. Hystim contains several ingredients, both time-tested (caffeine, theobromine and Hyperzine A) and cutting edge (theacrine and N- phenethyldimethylamine) that synergistically stimulate central nervous system arousal and enhance mood. So your muscles can keep up, we’ve also included a convenient dose of ß-alanine in HyStim, to build and maintain muscle carnosine levels, and thus buffering capacity and gym performance.

Pre-Workout Brain Boosting Ingredients:

We couldn’t call this product HyStim if we didn’t include caffeine (350mg of caffeine anhydrous), perhaps the world’s most popular1,2 energy booster3. Caffeine has a wide variety of ergogenic effects4,5 and is both thermogenic6, and lipolytic7, making it a viable staple for any fat loss regimen.

If you’re familiar with Granite Supplement’s line, you know that several of our products showcase what may be the “cleanest” over-the-counter “stimulant” of them all: Theacrine (as 125mg of Tasteless TeaCrine® per dose). Theacrine improves mood, focus, subjective feelings of energy, and motivation to exercise, but actually decreases anxiety8. Even after months of daily use (300mg), TeaCrine® does not lose its effectiveness or hook you into a nasty habit9 [which often happens with caffeine5,10]. [On the other hand, co-administering TeaCrine® with caffeine may actually prevent de-sensitization11.]

The HyStim “alkaloid trinity” is topped off by theobromine (100mg), another mood booster for some individuals12-14 that counterbalances caffeine’s hypertensive (blood pressure elevating) effect15,16. It’s possible that theobromine may synergize with caffeine to promote arousal17 but reduce perceived exertion during exercise because it’s also a bronchodilator11,18-21.

But wait, there’s more! We’ve quadrupled down to ensure HyStim puts you in the right mood to train, by including Huperzia Serrata [the Chinese herb known as Qian Ceng Ta 22], standardized for 1% Huperzine A (yielding 100μg). Hyperzine A is rapidly absorbed 23 and inhibits the acetylcholinesterase enzyme 24,25, thus prolonging the effect of acetylcholine (ACh) in the synapse. Huperzine-A shows promise in improving cognition, mood and spontaneous activity in Alzheimer’s patients (~100-800μg/day) with minimal side effects 22,26,27, but Huperzine A isn’t just for aging brains: Twice / day dosing of 50μg improved memory and learning in middle school students as well 28. As a bonus, Huperzine A seems to be brain healthy, as it protects neurons against injury by a variety of toxins and stresses 22,29.

There’s a new kid on the PEA block and he’s part of the HyStim gang: N-Phenethyldimethylamine (150mg, as citrate salt derived from Eria Jarensis) is a phenylethylamine (PEA) compound 30,31, meaning it’s structurally similar to tyramine (found in cheese, for instance 31], hordenine[found in barley32 Hapke, 1995 #12129}] and many other biogenic amines, such as those found in chocolate 33,34. You’re probably familiar with the PEA derivatives found in our bodies are the catecholamine neurotransmitters (noradrenaline, adrenaline and dopamine)… The mechanistic evidence other several other PEAs suggests that N- Phenylethyldimethylamine’s stimulant actions come via modulating the metabolism of these catecholamines and/or binding to their receptors31.

Intra-Workout Performance Ingredients:

ß-Alanine supplementation fills your muscles’ carnosine tanks35,36, topping off your capacity to buffer acidity during high intensity efforts37. This means a stronger kick at the finish line38, better performance lifting weights35 or doing intervals39, and more importantly, more muscle mass39. The 1.6g dose of ß- alanine found in HyStim alone should produce a modest increase in muscle carnosine levels40, but limit the skin-tingling (paresthesia) side effect37,40 that larger doses of ß-alanine are famous for. [NOTE: Ergogenic effects from ß-alanine are a probably a matter of increasing muscle carnosine over time41. Supplementing with an additional ~3-4g of ß-alanine, spread throughout the day should produce much higher carnosine levels more quickly35,36, but a cumulative dose of ~180g, spread over a longer loading period, should also do the trick41,42.]

Whats the recommended dosage for HyStim?

Mix one scoop (4.3 grams) into 12-16 ounces of cold water and shake or stir. Consume 15 minutes before exercise. Do not consume HyStim within 6 hours prior to taking HyStim. As always, for stronger and sweeter flavor use less water and for weaker use more water. Adjust to the way you like and enjoy.

Research and References

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